Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
Upregulated in class | transDMproB |
GeneSet | INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY |
Enrichment Score (ES) | 0.61367434 |
Normalized Enrichment Score (NES) | 1.4846165 |
Nominal p-value | 0.0 |
FDR q-value | 0.26047847 |
FWER p-Value | 0.99 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PSMA3 | 9632 5298 | 7 | 5.394 | 0.0739 | Yes | ||
2 | GFRA1 | 9015 | 28 | 4.130 | 0.1297 | Yes | ||
3 | KIT | 16823 | 41 | 3.739 | 0.1805 | Yes | ||
4 | STAT4 | 14251 9907 | 76 | 2.969 | 0.2196 | Yes | ||
5 | MAPK9 | 1233 20903 1383 | 85 | 2.800 | 0.2577 | Yes | ||
6 | LCK | 15746 | 101 | 2.651 | 0.2934 | Yes | ||
7 | MAPKAPK2 | 13838 | 146 | 2.333 | 0.3232 | Yes | ||
8 | IL12A | 4913 | 186 | 2.203 | 0.3514 | Yes | ||
9 | SOCS2 | 5694 | 265 | 1.860 | 0.3728 | Yes | ||
10 | JAK3 | 9198 4936 | 338 | 1.648 | 0.3915 | Yes | ||
11 | MAP4K2 | 6457 | 348 | 1.618 | 0.4133 | Yes | ||
12 | CAMK2B | 20536 | 391 | 1.552 | 0.4324 | Yes | ||
13 | STAT1 | 3936 5524 | 443 | 1.477 | 0.4500 | Yes | ||
14 | PSMB9 | 23021 | 482 | 1.379 | 0.4669 | Yes | ||
15 | STAT3 | 5525 9906 | 534 | 1.263 | 0.4815 | Yes | ||
16 | MAP3K3 | 20626 | 561 | 1.226 | 0.4970 | Yes | ||
17 | PRKCH | 21246 | 909 | 0.818 | 0.4894 | Yes | ||
18 | PSMB2 | 2324 16078 | 916 | 0.807 | 0.5002 | Yes | ||
19 | PDPK1 | 23097 | 950 | 0.777 | 0.5091 | Yes | ||
20 | MAP3K5 | 20079 11166 | 996 | 0.734 | 0.5168 | Yes | ||
21 | MAP3K11 | 11163 | 1013 | 0.714 | 0.5258 | Yes | ||
22 | RIPK1 | 5381 | 1092 | 0.657 | 0.5306 | Yes | ||
23 | MAP4K3 | 22887 | 1118 | 0.641 | 0.5381 | Yes | ||
24 | STAT5A | 20664 | 1181 | 0.601 | 0.5430 | Yes | ||
25 | MAPK14 | 23313 | 1184 | 0.600 | 0.5511 | Yes | ||
26 | TNFSF10 | 15626 | 1198 | 0.592 | 0.5586 | Yes | ||
27 | PRKCD | 21897 | 1237 | 0.576 | 0.5645 | Yes | ||
28 | SOCS3 | 20131 | 1254 | 0.567 | 0.5714 | Yes | ||
29 | AKT3 | 13739 982 | 1267 | 0.562 | 0.5785 | Yes | ||
30 | MAP3K14 | 11998 | 1289 | 0.549 | 0.5849 | Yes | ||
31 | CDK4 | 3424 19859 | 1298 | 0.546 | 0.5920 | Yes | ||
32 | PSMB8 | 5000 | 1331 | 0.532 | 0.5976 | Yes | ||
33 | KRAS | 9247 | 1356 | 0.521 | 0.6035 | Yes | ||
34 | ACVR1 | 4334 | 1466 | 0.479 | 0.6041 | Yes | ||
35 | GSK3B | 22761 | 1631 | 0.404 | 0.6008 | Yes | ||
36 | PAK4 | 17909 | 1643 | 0.400 | 0.6057 | Yes | ||
37 | JAK1 | 15827 | 1686 | 0.384 | 0.6087 | Yes | ||
38 | MKNK2 | 3299 9392 | 1789 | 0.349 | 0.6080 | Yes | ||
39 | TEC | 16514 | 1837 | 0.330 | 0.6100 | Yes | ||
40 | PTK2B | 21776 | 1990 | 0.287 | 0.6057 | Yes | ||
41 | STAT2 | 19840 | 2087 | 0.261 | 0.6041 | Yes | ||
42 | MAP3K1 | 21348 | 2190 | 0.232 | 0.6017 | Yes | ||
43 | IKBKE | 67 | 2217 | 0.225 | 0.6034 | Yes | ||
44 | MAP2K3 | 20856 | 2228 | 0.221 | 0.6059 | Yes | ||
45 | BTK | 24061 | 2229 | 0.221 | 0.6090 | Yes | ||
46 | SOS2 | 21049 | 2262 | 0.214 | 0.6102 | Yes | ||
47 | CAMK2G | 21905 | 2283 | 0.210 | 0.6120 | Yes | ||
48 | IL1B | 14431 | 2372 | 0.186 | 0.6098 | Yes | ||
49 | PSMA2 | 9631 | 2384 | 0.184 | 0.6117 | Yes | ||
50 | IGF1R | 9157 | 2456 | 0.170 | 0.6102 | Yes | ||
51 | PSMB6 | 9634 | 2471 | 0.166 | 0.6117 | Yes | ||
52 | PSMB10 | 5299 18761 | 2491 | 0.162 | 0.6129 | Yes | ||
53 | CDK5 | 16591 | 2518 | 0.158 | 0.6137 | Yes | ||
54 | CDK2 | 3438 3373 19592 3322 | 2570 | 0.150 | 0.6130 | No | ||
55 | CDK6 | 16600 | 2602 | 0.144 | 0.6133 | No | ||
56 | GRB2 | 20149 | 2736 | 0.123 | 0.6078 | No | ||
57 | RIPK3 | 21817 | 2740 | 0.123 | 0.6093 | No | ||
58 | PAK1 | 9527 | 2868 | 0.104 | 0.6038 | No | ||
59 | FGFR2 | 1917 4722 1119 | 3186 | 0.073 | 0.5876 | No | ||
60 | MAPK13 | 23314 | 3196 | 0.072 | 0.5881 | No | ||
61 | FYN | 3375 3395 20052 | 3271 | 0.066 | 0.5850 | No | ||
62 | IL7 | 4921 | 3332 | 0.061 | 0.5826 | No | ||
63 | PSMB4 | 15252 | 3525 | 0.048 | 0.5728 | No | ||
64 | FLT1 | 3483 16287 | 3749 | 0.038 | 0.5612 | No | ||
65 | TYK2 | 12058 19215 | 3787 | 0.036 | 0.5597 | No | ||
66 | PDGFRB | 23539 | 3843 | 0.035 | 0.5572 | No | ||
67 | CSK | 8805 | 3887 | 0.033 | 0.5553 | No | ||
68 | ACVR2A | 8542 | 4035 | 0.028 | 0.5478 | No | ||
69 | ALK | 8574 | 4094 | 0.026 | 0.5450 | No | ||
70 | ACVR2B | 19276 | 4113 | 0.025 | 0.5443 | No | ||
71 | IL18 | 9172 | 4197 | 0.023 | 0.5402 | No | ||
72 | MAP3K8 | 23495 | 4233 | 0.022 | 0.5386 | No | ||
73 | CSNK1E | 6570 2211 11332 | 4238 | 0.022 | 0.5386 | No | ||
74 | PRKAR1B | 16320 | 4389 | 0.019 | 0.5308 | No | ||
75 | BMPR2 | 14241 4081 | 4432 | 0.018 | 0.5287 | No | ||
76 | CSF2 | 20454 | 4516 | 0.017 | 0.5245 | No | ||
77 | MAPK3 | 6458 11170 | 4552 | 0.016 | 0.5228 | No | ||
78 | TNF | 23004 | 4599 | 0.016 | 0.5205 | No | ||
79 | MAPK7 | 1381 20414 | 4636 | 0.015 | 0.5188 | No | ||
80 | PSMA6 | 21270 | 4710 | 0.015 | 0.5150 | No | ||
81 | TGFBR1 | 16213 10165 5745 | 4801 | 0.013 | 0.5103 | No | ||
82 | IL11 | 17981 | 4921 | 0.012 | 0.5040 | No | ||
83 | PRKCA | 20174 | 4949 | 0.012 | 0.5027 | No | ||
84 | MET | 17520 | 5337 | 0.010 | 0.4818 | No | ||
85 | PAK3 | 9528 | 5514 | 0.008 | 0.4724 | No | ||
86 | FGFR4 | 3226 | 5546 | 0.008 | 0.4708 | No | ||
87 | ACVRL1 | 22354 | 5592 | 0.008 | 0.4685 | No | ||
88 | PRKACA | 18549 3844 | 5640 | 0.008 | 0.4661 | No | ||
89 | SOS1 | 5476 | 5657 | 0.008 | 0.4653 | No | ||
90 | IL2 | 15354 | 5783 | 0.007 | 0.4586 | No | ||
91 | BMPR1B | 8661 15152 4451 | 5943 | 0.007 | 0.4501 | No | ||
92 | STAT5B | 20222 | 5994 | 0.006 | 0.4474 | No | ||
93 | SOCS6 | 12042 7044 | 6067 | 0.006 | 0.4436 | No | ||
94 | IFNB1 | 15846 | 6072 | 0.006 | 0.4435 | No | ||
95 | TGFBR2 | 2994 3001 10167 | 6464 | 0.005 | 0.4223 | No | ||
96 | PTPN11 | 5326 16391 9660 | 6520 | 0.004 | 0.4194 | No | ||
97 | KDR | 16509 | 7480 | 0.002 | 0.3674 | No | ||
98 | FASLG | 13789 | 7513 | 0.002 | 0.3657 | No | ||
99 | PRKCI | 9576 | 7683 | 0.001 | 0.3565 | No | ||
100 | AKT2 | 4365 4366 | 7867 | 0.001 | 0.3466 | No | ||
101 | NGFR | 5174 | 8055 | 0.000 | 0.3364 | No | ||
102 | PRKG1 | 5289 | 8458 | -0.001 | 0.3146 | No | ||
103 | THPO | 22636 | 8587 | -0.001 | 0.3077 | No | ||
104 | IL12B | 20918 | 8591 | -0.001 | 0.3075 | No | ||
105 | CSF3 | 1394 20671 | 8594 | -0.001 | 0.3074 | No | ||
106 | EPO | 8911 | 8838 | -0.002 | 0.2943 | No | ||
107 | SOCS5 | 1619 23141 | 8896 | -0.002 | 0.2912 | No | ||
108 | KITLG | 19889 3342 | 8902 | -0.002 | 0.2909 | No | ||
109 | PSMA1 | 1627 17669 | 8927 | -0.002 | 0.2897 | No | ||
110 | IL9 | 21444 | 9030 | -0.002 | 0.2842 | No | ||
111 | ITK | 4934 | 9321 | -0.003 | 0.2684 | No | ||
112 | CD40LG | 24330 | 9344 | -0.003 | 0.2673 | No | ||
113 | MAP2K4 | 20405 | 9477 | -0.003 | 0.2602 | No | ||
114 | PRKCQ | 2873 2831 | 9877 | -0.004 | 0.2386 | No | ||
115 | PRKCE | 9575 | 9884 | -0.004 | 0.2383 | No | ||
116 | RPS6KA3 | 8490 | 9927 | -0.004 | 0.2361 | No | ||
117 | LTA | 23003 | 10055 | -0.004 | 0.2292 | No | ||
118 | SRC | 5507 | 10223 | -0.005 | 0.2202 | No | ||
119 | CAMK2A | 2024 23541 1980 | 10341 | -0.005 | 0.2139 | No | ||
120 | IL1A | 4915 | 10423 | -0.005 | 0.2096 | No | ||
121 | MOS | 16254 | 10557 | -0.006 | 0.2025 | No | ||
122 | PDGFRA | 16824 | 10973 | -0.007 | 0.1800 | No | ||
123 | EGFR | 1329 20944 | 11167 | -0.008 | 0.1697 | No | ||
124 | FGFR1 | 3789 8968 | 11379 | -0.008 | 0.1583 | No | ||
125 | MAPKAPK5 | 16387 | 11527 | -0.009 | 0.1505 | No | ||
126 | CDK7 | 21365 | 11610 | -0.009 | 0.1462 | No | ||
127 | MAPK10 | 11169 | 11763 | -0.010 | 0.1381 | No | ||
128 | WEE1 | 18127 | 11768 | -0.010 | 0.1380 | No | ||
129 | RPS6KA2 | 9759 9758 | 11842 | -0.010 | 0.1342 | No | ||
130 | INSR | 18950 | 12468 | -0.014 | 0.1004 | No | ||
131 | SOCS7 | 5308 20679 | 12483 | -0.014 | 0.0998 | No | ||
132 | FGFR3 | 8969 3566 | 12834 | -0.016 | 0.0811 | No | ||
133 | RIPK2 | 2528 15935 | 12909 | -0.017 | 0.0773 | No | ||
134 | FLT4 | 20904 1461 | 12999 | -0.017 | 0.0727 | No | ||
135 | BMPR1A | 8660 4450 | 13006 | -0.018 | 0.0726 | No | ||
136 | IL6 | 16895 | 13211 | -0.019 | 0.0618 | No | ||
137 | RPS6KB2 | 7198 | 13235 | -0.020 | 0.0608 | No | ||
138 | AKT1 | 8568 | 13355 | -0.021 | 0.0546 | No | ||
139 | IL4 | 9174 | 13402 | -0.021 | 0.0524 | No | ||
140 | ZAP70 | 14271 4042 | 13496 | -0.022 | 0.0477 | No | ||
141 | IL3 | 20453 | 13638 | -0.025 | 0.0404 | No | ||
142 | IL17A | 14289 | 13650 | -0.025 | 0.0401 | No | ||
143 | IKBKG | 2570 2562 4908 | 13789 | -0.027 | 0.0330 | No | ||
144 | LIF | 956 667 20960 | 13887 | -0.028 | 0.0281 | No | ||
145 | IL5 | 20884 10220 | 13948 | -0.030 | 0.0253 | No | ||
146 | PLK1 | 9590 5266 | 13974 | -0.030 | 0.0243 | No | ||
147 | IFNG | 19869 | 13979 | -0.030 | 0.0245 | No | ||
148 | IL15 | 18826 3801 | 14186 | -0.034 | 0.0138 | No | ||
149 | JAK2 | 23893 9197 3706 | 14194 | -0.034 | 0.0139 | No | ||
150 | PRKAR2B | 5288 2107 | 14236 | -0.035 | 0.0122 | No | ||
151 | PRKG2 | 74 | 14296 | -0.036 | 0.0095 | No | ||
152 | MAPK11 | 2264 9618 22163 | 14587 | -0.045 | -0.0056 | No | ||
153 | MNAT1 | 9396 2161 | 14660 | -0.047 | -0.0089 | No | ||
154 | MAP3K2 | 11165 | 14854 | -0.054 | -0.0186 | No | ||
155 | ARAF | 24367 | 14892 | -0.055 | -0.0199 | No | ||
156 | RAF1 | 17035 | 15064 | -0.065 | -0.0283 | No | ||
157 | MAP2K6 | 20614 1414 | 15246 | -0.076 | -0.0371 | No | ||
158 | RPS6KA1 | 15725 | 15263 | -0.077 | -0.0369 | No | ||
159 | MAP3K7 | 16255 | 15267 | -0.077 | -0.0360 | No | ||
160 | LTK | 14467 | 15367 | -0.083 | -0.0402 | No | ||
161 | PAK2 | 10310 5875 | 15410 | -0.087 | -0.0413 | No | ||
162 | IL13 | 20461 | 15628 | -0.108 | -0.0516 | No | ||
163 | IRAK4 | 22379 11185 | 15711 | -0.117 | -0.0544 | No | ||
164 | MAP3K12 | 6454 11164 | 15806 | -0.129 | -0.0577 | No | ||
165 | MAPK8 | 6459 | 15826 | -0.132 | -0.0570 | No | ||
166 | PSMB1 | 23118 | 15858 | -0.137 | -0.0568 | No | ||
167 | MAP2K1 | 19082 | 15878 | -0.140 | -0.0559 | No | ||
168 | HRAS | 4868 | 16140 | -0.184 | -0.0675 | No | ||
169 | PSMA5 | 6464 | 16209 | -0.197 | -0.0685 | No | ||
170 | GRK6 | 6449 | 16230 | -0.202 | -0.0668 | No | ||
171 | PRKCZ | 5260 | 16309 | -0.219 | -0.0680 | No | ||
172 | NRAS | 5191 | 16367 | -0.233 | -0.0679 | No | ||
173 | SOCS4 | 7424 | 16418 | -0.248 | -0.0672 | No | ||
174 | MAP2K2 | 19933 | 16484 | -0.264 | -0.0671 | No | ||
175 | PSMB3 | 11180 | 16533 | -0.276 | -0.0659 | No | ||
176 | MKNK1 | 2504 | 16601 | -0.293 | -0.0655 | No | ||
177 | CCNH | 7322 | 16640 | -0.306 | -0.0633 | No | ||
178 | PSMA4 | 11179 | 16697 | -0.318 | -0.0620 | No | ||
179 | PSMC1 | 9635 | 16701 | -0.319 | -0.0577 | No | ||
180 | SOCS1 | 4522 | 16716 | -0.323 | -0.0540 | No | ||
181 | PSMB7 | 2795 14598 | 16755 | -0.332 | -0.0515 | No | ||
182 | PSMB5 | 9633 | 16850 | -0.361 | -0.0517 | No | ||
183 | NLK | 5179 5178 | 16855 | -0.362 | -0.0469 | No | ||
184 | PLK3 | 15790 | 16969 | -0.397 | -0.0476 | No | ||
185 | SYK | 21636 | 16978 | -0.400 | -0.0425 | No | ||
186 | PSMA7 | 14318 | 17013 | -0.414 | -0.0386 | No | ||
187 | IKBKB | 4907 | 17370 | -0.562 | -0.0502 | No | ||
188 | PSMD2 | 10137 5724 | 17451 | -0.598 | -0.0463 | No | ||
189 | MAPK12 | 2182 2215 22164 | 17503 | -0.632 | -0.0404 | No | ||
190 | IRAK1 | 4916 | 17509 | -0.634 | -0.0319 | No | ||
191 | IL10 | 14145 1510 1553 22902 | 17539 | -0.650 | -0.0246 | No | ||
192 | CHUK | 23665 | 17636 | -0.706 | -0.0201 | No | ||
193 | PRKAR2A | 5287 | 17679 | -0.732 | -0.0123 | No | ||
194 | RYK | 19338 3870 | 17745 | -0.778 | -0.0051 | No | ||
195 | PTPN6 | 17002 | 18111 | -1.117 | -0.0095 | No | ||
196 | PTK2 | 22271 | 18549 | -2.677 | 0.0036 | No |