DatasetSet_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls
#transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls
#transDMproB_versus_transDMpreB_repos
Phenotypephenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos
Upregulated in classtransDMproB
GeneSetINOH_JAK-STAT PATHWAY AND REGULATION PATHWAY
Enrichment Score (ES)0.61367434
Normalized Enrichment Score (NES)1.4846165
Nominal p-value0.0
FDR q-value0.26047847
FWER p-Value0.99
Table: GSEA Results Summary



Fig 1: Enrichment plot: INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PSMA39632 529875.3940.0739Yes
2GFRA19015284.1300.1297Yes
3KIT16823413.7390.1805Yes
4STAT414251 9907762.9690.2196Yes
5MAPK91233 20903 1383852.8000.2577Yes
6LCK157461012.6510.2934Yes
7MAPKAPK2138381462.3330.3232Yes
8IL12A49131862.2030.3514Yes
9SOCS256942651.8600.3728Yes
10JAK39198 49363381.6480.3915Yes
11MAP4K264573481.6180.4133Yes
12CAMK2B205363911.5520.4324Yes
13STAT13936 55244431.4770.4500Yes
14PSMB9230214821.3790.4669Yes
15STAT35525 99065341.2630.4815Yes
16MAP3K3206265611.2260.4970Yes
17PRKCH212469090.8180.4894Yes
18PSMB22324 160789160.8070.5002Yes
19PDPK1230979500.7770.5091Yes
20MAP3K520079 111669960.7340.5168Yes
21MAP3K111116310130.7140.5258Yes
22RIPK1538110920.6570.5306Yes
23MAP4K32288711180.6410.5381Yes
24STAT5A2066411810.6010.5430Yes
25MAPK142331311840.6000.5511Yes
26TNFSF101562611980.5920.5586Yes
27PRKCD2189712370.5760.5645Yes
28SOCS32013112540.5670.5714Yes
29AKT313739 98212670.5620.5785Yes
30MAP3K141199812890.5490.5849Yes
31CDK43424 1985912980.5460.5920Yes
32PSMB8500013310.5320.5976Yes
33KRAS924713560.5210.6035Yes
34ACVR1433414660.4790.6041Yes
35GSK3B2276116310.4040.6008Yes
36PAK41790916430.4000.6057Yes
37JAK11582716860.3840.6087Yes
38MKNK23299 939217890.3490.6080Yes
39TEC1651418370.3300.6100Yes
40PTK2B2177619900.2870.6057Yes
41STAT21984020870.2610.6041Yes
42MAP3K12134821900.2320.6017Yes
43IKBKE6722170.2250.6034Yes
44MAP2K32085622280.2210.6059Yes
45BTK2406122290.2210.6090Yes
46SOS22104922620.2140.6102Yes
47CAMK2G2190522830.2100.6120Yes
48IL1B1443123720.1860.6098Yes
49PSMA2963123840.1840.6117Yes
50IGF1R915724560.1700.6102Yes
51PSMB6963424710.1660.6117Yes
52PSMB105299 1876124910.1620.6129Yes
53CDK51659125180.1580.6137Yes
54CDK23438 3373 19592 332225700.1500.6130No
55CDK61660026020.1440.6133No
56GRB22014927360.1230.6078No
57RIPK32181727400.1230.6093No
58PAK1952728680.1040.6038No
59FGFR21917 4722 111931860.0730.5876No
60MAPK132331431960.0720.5881No
61FYN3375 3395 2005232710.0660.5850No
62IL7492133320.0610.5826No
63PSMB41525235250.0480.5728No
64FLT13483 1628737490.0380.5612No
65TYK212058 1921537870.0360.5597No
66PDGFRB2353938430.0350.5572No
67CSK880538870.0330.5553No
68ACVR2A854240350.0280.5478No
69ALK857440940.0260.5450No
70ACVR2B1927641130.0250.5443No
71IL18917241970.0230.5402No
72MAP3K82349542330.0220.5386No
73CSNK1E6570 2211 1133242380.0220.5386No
74PRKAR1B1632043890.0190.5308No
75BMPR214241 408144320.0180.5287No
76CSF22045445160.0170.5245No
77MAPK36458 1117045520.0160.5228No
78TNF2300445990.0160.5205No
79MAPK71381 2041446360.0150.5188No
80PSMA62127047100.0150.5150No
81TGFBR116213 10165 574548010.0130.5103No
82IL111798149210.0120.5040No
83PRKCA2017449490.0120.5027No
84MET1752053370.0100.4818No
85PAK3952855140.0080.4724No
86FGFR4322655460.0080.4708No
87ACVRL12235455920.0080.4685No
88PRKACA18549 384456400.0080.4661No
89SOS1547656570.0080.4653No
90IL21535457830.0070.4586No
91BMPR1B8661 15152 445159430.0070.4501No
92STAT5B2022259940.0060.4474No
93SOCS612042 704460670.0060.4436No
94IFNB11584660720.0060.4435No
95TGFBR22994 3001 1016764640.0050.4223No
96PTPN115326 16391 966065200.0040.4194No
97KDR1650974800.0020.3674No
98FASLG1378975130.0020.3657No
99PRKCI957676830.0010.3565No
100AKT24365 436678670.0010.3466No
101NGFR517480550.0000.3364No
102PRKG152898458-0.0010.3146No
103THPO226368587-0.0010.3077No
104IL12B209188591-0.0010.3075No
105CSF31394 206718594-0.0010.3074No
106EPO89118838-0.0020.2943No
107SOCS51619 231418896-0.0020.2912No
108KITLG19889 33428902-0.0020.2909No
109PSMA11627 176698927-0.0020.2897No
110IL9214449030-0.0020.2842No
111ITK49349321-0.0030.2684No
112CD40LG243309344-0.0030.2673No
113MAP2K4204059477-0.0030.2602No
114PRKCQ2873 28319877-0.0040.2386No
115PRKCE95759884-0.0040.2383No
116RPS6KA384909927-0.0040.2361No
117LTA2300310055-0.0040.2292No
118SRC550710223-0.0050.2202No
119CAMK2A2024 23541 198010341-0.0050.2139No
120IL1A491510423-0.0050.2096No
121MOS1625410557-0.0060.2025No
122PDGFRA1682410973-0.0070.1800No
123EGFR1329 2094411167-0.0080.1697No
124FGFR13789 896811379-0.0080.1583No
125MAPKAPK51638711527-0.0090.1505No
126CDK72136511610-0.0090.1462No
127MAPK101116911763-0.0100.1381No
128WEE11812711768-0.0100.1380No
129RPS6KA29759 975811842-0.0100.1342No
130INSR1895012468-0.0140.1004No
131SOCS75308 2067912483-0.0140.0998No
132FGFR38969 356612834-0.0160.0811No
133RIPK22528 1593512909-0.0170.0773No
134FLT420904 146112999-0.0170.0727No
135BMPR1A8660 445013006-0.0180.0726No
136IL61689513211-0.0190.0618No
137RPS6KB2719813235-0.0200.0608No
138AKT1856813355-0.0210.0546No
139IL4917413402-0.0210.0524No
140ZAP7014271 404213496-0.0220.0477No
141IL32045313638-0.0250.0404No
142IL17A1428913650-0.0250.0401No
143IKBKG2570 2562 490813789-0.0270.0330No
144LIF956 667 2096013887-0.0280.0281No
145IL520884 1022013948-0.0300.0253No
146PLK19590 526613974-0.0300.0243No
147IFNG1986913979-0.0300.0245No
148IL1518826 380114186-0.0340.0138No
149JAK223893 9197 370614194-0.0340.0139No
150PRKAR2B5288 210714236-0.0350.0122No
151PRKG27414296-0.0360.0095No
152MAPK112264 9618 2216314587-0.045-0.0056No
153MNAT19396 216114660-0.047-0.0089No
154MAP3K21116514854-0.054-0.0186No
155ARAF2436714892-0.055-0.0199No
156RAF11703515064-0.065-0.0283No
157MAP2K620614 141415246-0.076-0.0371No
158RPS6KA11572515263-0.077-0.0369No
159MAP3K71625515267-0.077-0.0360No
160LTK1446715367-0.083-0.0402No
161PAK210310 587515410-0.087-0.0413No
162IL132046115628-0.108-0.0516No
163IRAK422379 1118515711-0.117-0.0544No
164MAP3K126454 1116415806-0.129-0.0577No
165MAPK8645915826-0.132-0.0570No
166PSMB12311815858-0.137-0.0568No
167MAP2K11908215878-0.140-0.0559No
168HRAS486816140-0.184-0.0675No
169PSMA5646416209-0.197-0.0685No
170GRK6644916230-0.202-0.0668No
171PRKCZ526016309-0.219-0.0680No
172NRAS519116367-0.233-0.0679No
173SOCS4742416418-0.248-0.0672No
174MAP2K21993316484-0.264-0.0671No
175PSMB31118016533-0.276-0.0659No
176MKNK1250416601-0.293-0.0655No
177CCNH732216640-0.306-0.0633No
178PSMA41117916697-0.318-0.0620No
179PSMC1963516701-0.319-0.0577No
180SOCS1452216716-0.323-0.0540No
181PSMB72795 1459816755-0.332-0.0515No
182PSMB5963316850-0.361-0.0517No
183NLK5179 517816855-0.362-0.0469No
184PLK31579016969-0.397-0.0476No
185SYK2163616978-0.400-0.0425No
186PSMA71431817013-0.414-0.0386No
187IKBKB490717370-0.562-0.0502No
188PSMD210137 572417451-0.598-0.0463No
189MAPK122182 2215 2216417503-0.632-0.0404No
190IRAK1491617509-0.634-0.0319No
191IL1014145 1510 1553 2290217539-0.650-0.0246No
192CHUK2366517636-0.706-0.0201No
193PRKAR2A528717679-0.732-0.0123No
194RYK19338 387017745-0.778-0.0051No
195PTPN61700218111-1.117-0.0095No
196PTK22227118549-2.6770.0036No
Table: GSEA details [plain text format]



Fig 2: INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY: Random ES distribution   
Gene set null distribution of ES for INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY